Sunday, May 18, 2014

Letter to the editor of the Lancet Journal of infectious diseases

Letter to the authors of a study which was about consolidating diagnosis and treatment of Lyme disease. You can read the abstract of the study down at the bottom of this article. Response by Lyme activist Carl Tuttle is at the top.

I'm posting this because the four links included in the response should be widely publicized and made available. They are packed with knowledge about the persistence of Borrelia species of bacteria. Please repost those links anywhere you can, if possible. They constitute convincing evidence of the ubiquity and resilience of the Borrelia spirochete.

An Arden-syntax-based clinical decision support framework for medical guidelines-lyme borreliosis as an example.

Seitinger A, Fehre K, Adlassnig KP, Rappelsberger A, Wurm E, Aberer E, Binder M.

To the authors of this abstract,

If Lyme disease was conceptualized to enable vaccine development then a one-size-fits-all Lyme treatment guideline makes perfect sense. A preventive vaccine for Lyme disease would not satisfy the FDA if a chronic persistent infection and seronegative disease exist.

If medical guidelines are based on this "conceptualized disease" how would Fuzzy Arden Syntax improve the overall usability of a clinical decision support system?

Ample evidence suggests that Lyme disease has been intentionally mishandled as no other infection is denied re-treatment when the same symptoms for which the diagnosis of Lyme disease was originally made persist or return. Until such time that there is a direct test (e.g. trail-marker), it seems more reasonable to conclude that persistent symptoms are due to persisting infection.

Oslo University biologists Morten Laane and Ivar Mysterud recently announced that Borrelia bacteria are capable of changing into cyst forms within an hour and that antibiotic medication is then unable to destroy them.

Pathologist Dr Alan MacDonald has compiled a list of 123 autopsy cases of Lyme borreliosis. The autopsy proves as no other evidence can that chronic Lyme Borreliosis in the human host is a reality, causing enormous disabilities, patient suffering, and life altering changes.

Chronic Lyme Borreliosis in the Human host: Autopsy Evidence from 123 peer reviewed published Autopsies:


In addition to Dr MacDonald's evidence of chronic Lyme disease from peer reviewed studies here are some additional studies to consider:

Persistent Lyme infection273 Peer-Reviewed Studies

Seronegativity in Lyme borreliosis103 Peer-Reviewed Studies

Congenital Transmission of Lyme28 Peer-Reviewed Studies

To complicate matters Lyme disease is not the only pathogen transmitted from a tick bite. Multiple pathogens can be transmitted simultaneously while treatment must be integrated to eradicate these pathogens. (Babesia, Bartonella, mycoplasma, Ehrlichia, etc.)

Your paper may need to be amended if the knowledge base includes questionable clinical guidelines for Lyme disease by the Infectious Disease Society of America. (IDSA Treatment Guidelines)

Respectfully Submitted,

Carl Tuttle
33 David Dr
Hudson, NH 03051
Website: New Hampshire Lyme Misdiagnosis

Petition: Calling for a Congressional investigation of the CDC, IDSA and ALDF

Letter to the Editor, The Lancet Infectious Diseases Published May 2012

Stud Health Technol Inform. 2014;198:125-32.

An Arden-syntax-based clinical decision support framework for medical guidelines-lymeborreliosis as an example.

Author information

  • 1Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria.
  • 2Medexter Healthcare GmbH, Vienna, Austria.
  • 3Section for Medical Expert and Knowledge-Based Systems, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Austria.
  • 4Department of Environmental Dermatology and Venereology, Medical University Graz, Austria.


Medicine is evolving at a very fast pace. The overwhelming quantity of new data compels the practician to be consistently informed about the most recent scientific advances. 
While medical guidelines have proven to be an acceptable tool for bringing new medical knowledge into clinical practice and also support medical personnel, reading them may be rather time-consuming. 
Clinical decision support systems have been developed to simplify this process. However, the implementation or adaptation of such systems for individual guidelines involves substantial effort. 
This paper introduces a clinical decision support platform that uses Arden Syntax to implement medical guidelines using client-server architecture. It provides a means of implementing different guidelines without the need for adapting the system's source code. 
To implement a prototype, three Lyme borreliosis guidelines were aggregated and a knowledge base created. The prototype employs transfer objects to represent any text-based medical guideline. 
As part of the implementation, we show how Fuzzy Arden Syntax can improve the overall usability of a clinical decision support system.
[PubMed - in process]

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