Thursday, August 27, 2015

Scientific evidence that Alzheimer's results from brain infection

There is scientific evidence that cases of Alzheimer's which are not genetically determined are caused by bacterial infection of the brain.  This comes from the neurologist J. Miklossy, and you may wish to read this brief summary before looking at the article itself (a link to the article is provided farther down in this message):

1. An average of 90% of autopsied Alzheimer's disease (AD) patient brains are found to be infected with pathogenic spirochetal bacteria. Lyme bacteria are found in 25% (this is 13 times higher than in the control population) of autopsied Alzheimer's brains. The mouth is another source of pathogenic spriochetes, and they can migrate from that location to the brain. Such bacteria are found in 93.7% of autopsied AD brains, but are found in only 33.3% of non-AD brains.  These percentages produce a statistically significant difference between the AD and normal populations.  

2. Lyme disease and syphilis are both caused by spirochetal (motile cork screw shaped) bacteria.

3. Syphilis is known to cause dementia. Also, Lyme disease (an infection by the spirochetal bacterium Borrelia burgdorferi, transmitted to humans by tick bite) is known to be capable of causing severe cognitive impairment.

4. The bacterial infection described above is co-located with the Alzheimer's plaques.

5. The A-Beta protein which accumulates in Alzheimer's brains is an anti-microbial protein (i.e. it can kill bacteria). This (along with #4 above) suggests that its proliferation may be a physiological  response to infection.

6. When mammalian neural cells are cultured with added Lyme bacteria, the characteristic pathological hallmarks of Alzheimer's disease (i.e plaque build-up, fibrils, etc.) are found to occur.

(Source for the above: Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria. Miklossy J. Journal of  Neuroinflammation. 2011; 8: 90. Published online 2011 August 4. doi: 10.1186/1742-2094-8-90 PMCID: PMC3171359)

There are two dramatic bar charts from the article comparing the incidence of bacterial infection between the AD and non-AD subjects:

The entire article can be found at:

One final resource comes from  the American pathologist Dr. Alan MacDonald, who discovered Lyme bacteria in the brains of Alzheimer patients, and has created 3 video presentations (total viewing time is about 80 minutes): (Preview)(Preview)  (Preview) (Preview)(Preview) (Preview)

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