Friday, July 26, 2013

Can Statins Fend Off Parkinson's Disease?

Published: Jul 25, 2013 | Updated: Jul 25, 2013
By Nancy Walsh, Staff Writer, MedPage Today
Reviewed by F. Perry Wilson, MD, MSCE; Instructor of Medicine, Perelman School of Medicine at the University of Pennsylvania
Action Points
Note that this large Chinese population study demonstrated that patients who continued their statin medication even after meeting LDL goals had a markedly reduced risk of Parkinson's disease.

Be aware that the nonrandomized nature of this study may introduce bias -- those who continue medications may engage in other healthy behaviors that reduce PD risk.
Patients who take statins to lower cholesterol may also protect themselves against Parkinson's disease, a Chinese population-based study suggested.

Compared with individuals who stopped taking statins when the low density lipoprotein target was met, those who continued on lipophilic statins had a hazard ratio of 0.42 (95% CI 0.27-0.64) for developing Parkinson's disease, according to Jou-Wei Lin, MD, PhD, of National Taiwan University in Taipei, and colleagues.

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