Monday, July 13, 2020

Genome-wide association studies have discovered hundreds of loci associated with complex brain disorders, but it remains unclear in which cell types these loci are active. Here we integrate genome-wide association study results with single-cell transcriptomic data from the entire mouse nervous system to systematically identify cell types underlying brain complex traits. We show that psychiatric disorders are predominantly associated with projecting excitatory and inhibitory neurons. Neurological diseases were associated with different cell types, which is consistent with other lines of evidence. Notably, Parkinson's disease was genetically associated not only with cholinergic and monoaminergic neurons (which include dopaminergic neurons) but also with enteric neurons and oligodendrocytes. Using post-mortem brain transcriptomic data, we confirmed alterations in these cells, even at the earliest stages of disease progression. Our study provides an important framework for understanding the cellular basis of complex brain maladies, and reveals an unexpected role of oligodendrocytes in Parkinson's disease.....

For the rest of the article:

https://www.nature.com/articles/s41588-020-0610-9

Doctors treat Parkinson’s with a novel brain cell transplant - STAT

https://www.statnews.com/2020/05/12/medical-first-parkinsons-brain-cell-transplant-stem-cells/

-bob

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Bob Cowart
Email: bob@cowart.com
Phone: 510-540-6667
Books: http://www.amazon.com/Robert-Cowart/e/B001HOJ3ZQ
Blog: http://bobcowart.blogspot.com
Twitter: @bobcowart

Monday, June 1, 2020

A Common Cough Syrup Drug Just Passed Another Trial as Parkinson's Treatment

https://www.sciencealert.com/drug-used-in-cough-syrup-for-decades-offers-new-hope-as-parkinson-s-treatment

Tuesday, May 26, 2020

Baking Soda Fights AutoImmune Disease | NaturalHealth365

Interesting article about study showing that baking soda can lower inflammation.

https://www.naturalhealth365.com/autoimmune-disease-baking-soda-3415.html

Thursday, April 30, 2020

A Clinical Diagnostic System for Late-Stage Neuro Lyme Borreliosis

A Clinical Diagnostic System for Late-Stage Neuropsychiatric Lyme Borreliosis Based upon an Analysis of 100 Patients

A study by the respected researcher Robert Bransfield and three others.

Healthcare | Free Full-Text |

https://www.mdpi.com/2227-9032/8/1/13

Thursday, April 23, 2020

The Sounds of Science

Maybe you've seen this before but it applies more with each passing day...

Monday, February 24, 2020

KosAbility: Parkinson's and Pesticides

Good article about the relationship between pesticides and Parkinson's disease.

https://www.dailykos.com/story/2016/9/25/1574133/-KosAbility-Parkinson-s-and-Pesticides

-Bob

Thursday, February 20, 2020

Mold, Air, Water, Sewage testing company

I've been looking for a company who can test air quality inside and outside of my house. I have wondered foe years whether my house's inside air was polluted, because in the AM when I awake, I often feel poisoned. I've looked into oxygen deprivation (which would cause CO2 poisoning) and mold, so far. I used Real Time labs for mold and micotoxin testing. I've treated my house and cars for micotoxins with chlorine dixoide gas. I still don't think I have found the culprit, but I suspect it has to do with gut dysbiosis more than with the external environment, though both may play a part.

In any case, the testing that these folks do might be among my next areas of inquiry.

-Bob

Why Test for Sewage Contamination?

Exposure to sewage contamination increases the risk of contracting diseases of the digestive system and other related illnesses. Potential disease causing organisms in sewage contamination include E. coli (some strains), Salmonella, and Shigella.

Sewage contamination can come from flooding events, failing septic systems, wastewater treatment plants, sewer overflows, vessel sewer discharge, runoff from surfaces, livestock, pets, wildlife, and humans.

The following bacteria are used as indicators of sewage contamination.

E. coli
Total coliforms
Fecal coliforms
Enterococci
Fecal Streptococcus.

These bacteria are not a health threat themselves but their presence is used as an indication of other potentially harmful bacteria.

Learn More...

General Bacteria Testing

Bacteria Testing

We perform various bacterial analytical tests at Mold & Bacteria Consulting Laboratories (MBL). We can test air samples (taken by an RCS sampler or an Anderson sampler), surface samples (taken by culture-swabs), and water samples, as well as many other types of samples. If you have a question regarding a particular test (including those not listed here), please ...

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MBL Among The CDC ELITE Certified Labs in Legionella Testing

Mold & Bacteria Consulting Laboratories (MBL) has certification in the analysis of Legionella bacteria by the prestigious Environmental Legionella Isolation Techniques Evaluation (ELITE) program of the US Centers for Diseases Control and Prevention (CDC). MBL is one of the only 3 Canadian independent laboratories having this industry-leading certification. MBL is also accredited by the Canadian Association For Laboratory Accreditation (CALA) ...

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Online Mold Inspection, Identification and Control Course

Our online mold training course is designed for people with busy schedules. The course is available 24/7 and can be taken in office or at home at any time of the day. Click Online Mold Training Course for more details.