Tuesday, December 15, 2015

Could Claritin Cure Lyme Disease?

I have posted about this before, but here is another publication on the same topic:

An OTC allergy medication may be able to kill the bacteria behind Lyme disease, bringing researchers closer to developing the first targeted therapy for the debilitating infection.

Since Lyme-causing Borrelia burgdorferi survive on manganese (Mn), researchers from the Stanford University School of Medicine hypothesized that blocking the bacteria's Mn transport protein, Borrelia metal transporter A (BmtA), would starve the bacteria and ultimately help cure the infection.

Among a shortlist of FDA-approved compounds that could potentially bind to the BmtA structure, the investigators determined that the antihistamine loratadine (Claritin)—and specifically its metabolite, desloratadine—were able to inhibit Mn from entering the cell walls of Borrelia, causing the bacteria to die in test tubes.

Read the full story:
http://www.pharmacytimes.com/news/could-claritin-cure-lyme-disease

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