A Clinical Diagnostic System for Late-Stage Neuropsychiatric Lyme Borreliosis Based upon an Analysis of 100 Patients
A study by the respected researcher Robert Bransfield and three others.
Healthcare | Free Full-Text |
Thursday, April 30, 2020
A Clinical Diagnostic System for Late-Stage Neuro Lyme Borreliosis
Thursday, April 23, 2020
Monday, February 24, 2020
KosAbility: Parkinson's and Pesticides
Good article about the relationship between pesticides and Parkinson's disease.
https://www.dailykos.com/story/2016/9/25/1574133/-KosAbility-Parkinson-s-and-Pesticides
-Bob
https://www.dailykos.com/story/2016/9/25/1574133/-KosAbility-Parkinson-s-and-Pesticides
-Bob
Thursday, February 20, 2020
Mold, Air, Water, Sewage testing company
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Tuesday, February 11, 2020
Microdose lithium formulation is capable of halting signs of advanced Alzheimer’s and improving cognition, reducing anxiety
Interesting and useful article about using Lithium orotate for anxiety treatment. Dosing, etc.
https://www.everywomanover29.com/blog/microdose-lithium-formulation-is-capable-of-halting-signs-of-advanced-alzheimers-and-improving-
https://www.everywomanover29.com/blog/microdose-lithium-formulation-is-capable-of-halting-signs-of-advanced-alzheimers-and-improving-
Saturday, January 25, 2020
Stomach bacteria may slow - and even reverse - Parkinson's disease
Stomach bacteria may slow - and even reverse - Parkinson's disease
The study is published in Cell Reports.
Study Finds
Sat, 18 Jan 2020 00:01 UTC
© tutul_1410/stock.adobe.com
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Study Finds
Sat, 18 Jan 2020 00:01 UTC
© tutul_1410/stock.adobe.com
Save
Parkinson's disease, a progressive nervous system disorder that greatly affects movement, can have a detrimental impact on one's quality of life. While there are medications available that help control its symptoms, there is no known cure for the disease. However, researchers from the Universities of Edinburgh and Dundee in Scotland recently identified a potential game changer in the fight against Parkinson's. A common probiotic, or "good" bacteria, found in our stomachs that helps maintain digestive health appears to be able to slow, and even reverse, the accumulation of a protein known to be associated with Parkinson's.
The groundwork for these findings were put in place by prior research that had identified a connection between brain function and gut bacteria. Now, using a group of roundworms, this study has discovered that the probiotic called Bacillus subtilis is capable of stopping the formation of toxic clumps in the brain that impede the flow of dopamine. Dopamine, besides its other uses, is integral to coordinating movement.
Within the brains of Parkinson's patients, the protein known as alpha-synuclein builds up, forming these aforementioned toxic clumps. These clumps then cause the death of nerve cells that should be producing dopamine. It's the loss of these very cells that cause the trademark symptoms of Parkinson's, such as shaking or overall slowness of movement.
The research team used a genetically altered group of roundworms capable of producing the human version of clump-forming alpha-synuclein. These worms were fed a variety of different over-the-counter probiotics, in an effort to see if any of them influenced subsequent clump formation.
The results of the experiment revealed that Bacillus subtilis had a robust protective effect that prevented the buildup of the alpha-synuclein protein. The probiotic even was able to do away with some pre-existing clumps that had already formed within the worms. After being given Bacillus subtilis, the worms movements immediately improved.
"The results provide an opportunity to investigate how changing the bacteria that make up our gut microbiome affects Parkinson's. The next steps are to confirm these results in mice, followed by fast-tracked clinical trials since the probiotic we tested is already commercially available," says Lead researcher Dr. Maria Doitsidou, of the Centre for Discovery Brain Sciences at the University of Edinburgh, in a release.
This piece of research is just the latest in a string of studies over the past few years indicating that the gut microbiome residing in each one our stomachs plays a critical role in brain function.
"Parkinson's is the fastest growing neurological condition in the world. Currently there is no treatment that can slow, reverse or protect someone from its progression but by funding projects like this, we're bringing forward the day when there will be," comments Dr Beckie Port, Research Manager at Parkinson's UK. "Changes in the microorganisms in the gut are believed to play a role in the initiation of Parkinson's in some cases and are linked to certain symptoms, that's why there is ongoing research into gut health and probiotics.
"The results from this study are exciting as they show a link between bacteria in the gut and the protein at the heart of Parkinson's, alpha synuclein. Studies that identify bacteria that are beneficial in Parkinson's have the potential to not only improve symptoms but could even protect people from developing the condition in the first place," she concludes.
The study is published in Cell Reports.
Comment: See also:
The groundwork for these findings were put in place by prior research that had identified a connection between brain function and gut bacteria. Now, using a group of roundworms, this study has discovered that the probiotic called Bacillus subtilis is capable of stopping the formation of toxic clumps in the brain that impede the flow of dopamine. Dopamine, besides its other uses, is integral to coordinating movement.
Within the brains of Parkinson's patients, the protein known as alpha-synuclein builds up, forming these aforementioned toxic clumps. These clumps then cause the death of nerve cells that should be producing dopamine. It's the loss of these very cells that cause the trademark symptoms of Parkinson's, such as shaking or overall slowness of movement.
The research team used a genetically altered group of roundworms capable of producing the human version of clump-forming alpha-synuclein. These worms were fed a variety of different over-the-counter probiotics, in an effort to see if any of them influenced subsequent clump formation.
The results of the experiment revealed that Bacillus subtilis had a robust protective effect that prevented the buildup of the alpha-synuclein protein. The probiotic even was able to do away with some pre-existing clumps that had already formed within the worms. After being given Bacillus subtilis, the worms movements immediately improved.
"The results provide an opportunity to investigate how changing the bacteria that make up our gut microbiome affects Parkinson's. The next steps are to confirm these results in mice, followed by fast-tracked clinical trials since the probiotic we tested is already commercially available," says Lead researcher Dr. Maria Doitsidou, of the Centre for Discovery Brain Sciences at the University of Edinburgh, in a release.
This piece of research is just the latest in a string of studies over the past few years indicating that the gut microbiome residing in each one our stomachs plays a critical role in brain function.
"Parkinson's is the fastest growing neurological condition in the world. Currently there is no treatment that can slow, reverse or protect someone from its progression but by funding projects like this, we're bringing forward the day when there will be," comments Dr Beckie Port, Research Manager at Parkinson's UK. "Changes in the microorganisms in the gut are believed to play a role in the initiation of Parkinson's in some cases and are linked to certain symptoms, that's why there is ongoing research into gut health and probiotics.
"The results from this study are exciting as they show a link between bacteria in the gut and the protein at the heart of Parkinson's, alpha synuclein. Studies that identify bacteria that are beneficial in Parkinson's have the potential to not only improve symptoms but could even protect people from developing the condition in the first place," she concludes.
The study is published in Cell Reports.
Comment: See also:
Thursday, January 16, 2020
Commentary: Lyme disease led to my daughter’s death. Join the fight against tick-borne disease | CalMatters
Bad news, good news.
By Jody Hudson, Special to CalMatters
My cause is personal, and my goal will not be deterred as I, and those joining with me, work to see that no other person suffers the way my daughter did.
A small tick bit her. That eventually led to her death. In 21st Century America, this should not have happened.
Alex Hudson's story exposes a medical system that remains unprepared to deal with debilitating illnesses that tick bites bring, including Lyme disease.
In 2018, at age 22, Alex lost her battle with Lyme disease and the resulting Mast Cell Activation Syndrome, which caused her body to have an allergic-like reaction to almost anything she ate or drank.
Two-hundred children a day are diagnosed with Lyme disease. The U.S. Centers for
Disease Control and Prevention reports that cases of tick borne diseases had more than doubled from 2004 to 2016, from 22,000 to 48,000.
Lyme disease accounted for 82% of all tick-borne diseases.
But you would never know when it comes to on-the-ground medical care. Alex spent a decade being shuttled….
TO READ THE REST OF THE STORY, CLICK BELOW:
•••••••••••
--Bob Cowart
--Bob Cowart
Friday, December 27, 2019
New book about deficiencies in generic drugs
There are many deficiencies in international generic drugs. This book addresses some of these issues.
In this sometimes frightening book, Eban delves into the dangerous market of generic pharmaceutical drugs.
https://www.foreignaffairs.com/reviews/capsule-review/2019-12-10/bottle-lies-inside-story-generic-drug-boom
Wednesday, December 18, 2019
Sunday, December 1, 2019
Deep Brain Stimulation impacts ability to swim
The electronic implants reduced Parkinson's symptoms, but also erased some patients' ability to swim.
(C) NY Times
- A lifelong swimmer leapt into deep water near his lakeside home, and was horrified to find himself completely unable to swim. Had his wife not rescued him, he might have drowned.He had recently received an electronic brain implant to control tremors and other symptoms of Parkinson's disease, and somehow the signals from the device had knocked out his ability to coordinate his arms and legs for swimming.
Three of them tried turning off the stimulators, and immediately could swim again, according to an article in the journal Neurology by a medical team from the University of Zurich.
Read the rest of the story:
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Treating Parkinson's with electrical spinal implant 'transforms lives'
Scientists discover mounting evidence that Parkinson's starts in the gut - not the brain
Smell of skin could lead to early diagnosis for Parkinson's
The appendix implicated in Parkinson's disease
Risk of Parkinson's disease increases with statin or 'cholesterol-lowering' drug use
Parkinson's disease may be triggered by virus that kills 'good bacteria' in the gut